Hua Chenyu has a strange shape.

1905 movie network news February 7th is Hua Chenyu’s 28th birthday. This afternoon, he took a photo in Weibo to thank his fans for their birthday wishes, and wrote: "Thank you, Happy Birthday and Happy Year of the Dog! ! ！”In the photo, Hua Chenyu is wearing a sweater with a cartoon pattern and a pair of loose jeans. The sunshine is handsome, but his photo pose is strange, with his mouth open, his head tilted, his waist bent and his hands drooping, which is very funny.

Hua Chenyu thanks the fans for taking photos on his 28th birthday.

Netizens have left messages saying: "You said! Did you leave your clothes in Beijing? " "Happy birthday! I wish you more and more fat in 18 years. "

　　Shanghai Pentium Group Co., Ltd., namely Shanghai Pentium Enterprise (Group) Co., Ltd., is a comprehensive high-tech enterprise integrating R&D, manufacturing and sales of household appliances. Products include a series of small kitchen appliances mainly based on induction cookers, rice cookers and water dispensers, and a series of personal care products mainly based on razors and hair dryers. With strategic vision and unremitting efforts, after more than ten years of steady development, Pentium has now developed into a first-class professional brand operator of small household appliances in China. POVOS Pentium has successively won the honorary titles of "Shanghai Famous Trademark", "Shanghai Famous Brand", "China Well-known Trademark", "National Inspection Exemption for Product Quality" and "2008 National Customer Satisfaction Enterprise". Pentium induction cooker, Pentium rice cooker, Pentium electric pressure cooker and Pentium water dispenser were recognized by China Industry Enterprise Information Publishing Center as the top three in the country in 2009, and Pentium shaver ranked fourth in the country in 2009.

Enterprise strength

Focus on independent research and development

　　Paying attention to the improvement of independent products, Pentium has established three of the most advanced research and development centers for small household appliances in the world, and set up a "special award fund for scientific and technological innovation" to commend outstanding scientific and technological research and development projects. At present, there are more than 170 international and domestic invention patents, utility model patents and appearance patents. Pioneering the technology of 4D floating structure of shaver, filling the gap in the industry and being at the leading level in the world.

National distribution of marketing network

　　Pentium adheres to the three-arrow market development strategy of "brand building through terminal channels, sales through circulation channels and market grabbing through emerging channels", and has an excellent marketing team, innovative marketing ideas and a nationwide marketing network.

Offline marketing network

　　Offline market products have covered nearly 30 provinces, cities and autonomous regions in China. At present, nine direct and joint-venture sales companies, including Shanghai Pentium, Beijing Pentium, Guangzhou Pentium, Henan Pentium, Liaoning Pentium, Yunnan Pentium, Fujian Pentium, Wenzhou Pentium and Jiaxing Pentium, have been established, and 33 commercial offices in six major marketing regions have been established, with more than 200 first-class agents, more than 5,500 retail terminals and more than 3,000 after-sales service outlets. At the same time, it has reached a strategic alliance and cooperation relationship with well-known home appliance chain enterprises and commercial supermarket systems at home and abroad. These include RT Mart, Wal-Mart, Carrefour, Metro, Gome, Suning Appliance, Lotus at the beginning of the month, Century Lianhua and so on. Excellent channel resources and terminal networks all over the country provide a strong market foundation for the expansion of Pentium.

Online marketing network (e-commerce)

　　From the second half of 2011, the online market launched e-commerce, completed the whole network layout, successively established a big Taobao system, deeply cultivated B2C platforms such as JD.COM, Yixun, Amazon, No.1 Store and Suning.cn, integrated mobile e-commerce such as Juhua, Vipshop, Meituan and Jumei, vigorously expanded O2O pan-e-commerce systems such as 2688 and Bank, operated through multiple channels, and established strategic cooperation relations with mainstream platforms of the whole network. In 2012, Pentium took e-commerce as its enterprise transformation and upgrading strategy, and relied on innovative marketing concepts to build a flexible supply chain oriented to market demand. The online market was linked with the whole network, and refined operation was promoted, with an annual growth rate of 500%. It won the Tmall Most Growing Brand Award and became the fastest growing brand in the personal care industry. In the same year, the strategic layout of POVOS international brand was completed by laying out POVOS overseas, building multinational e-commerce, and inciting the global market with low-cost and low-risk e-commerce trading. At present, the products have been exported to more than 40 countries overseas.

Gift marketing network

　　In view of the characteristics of personal care products suitable for group purchase gift channels, Pentium has made great efforts to develop and attach importance to group purchase gift channels, gradually planned and explored a new way for group purchase gift, implemented professional group purchase expansion, customized product mix and suit customization according to customers’ specialized needs, and created new sales growth points flexibly and orderly, becoming strategic partners of well-known domestic enterprises such as China Mobile Communications, China Unicom, China Telecom, China Merchants Bank, China Ping An, Shanghai Pudong Development Bank and Spring Airlines.

Television shopping marketing network

　　Emerging channel TV shopping, from the only three shopping platforms, namely Happy Shopping, Yangguang Shopping and Oriental Shopping, has developed into cooperation with nearly 40 stations across the country, and it is broadcasted 24 hours a day, covering the national TV audience.

Overseas marketing network

　　Realizing the synchronous growth of domestic and foreign sales is Pentium’s strategic development goal. Since its establishment three years ago, overseas offline markets have spread all over the world on seven continents, with 94 customers, and have become strategic partners with many well-known international brands and retailers, such as CONAIR,SEB,METRO,carrefour, tesco and auchan. Sales performance has doubled year by year, and in 2012 and 2013, it was recognized as "AAA credit rating enterprise" by China Chamber of Commerce for Import and Export of Mechanical and Electrical Appliances for two consecutive years. It was awarded as "2012 Shanghai Export Famous Brand" by Shanghai Commercial Committee.

Strong production base

　　Pentium has the first most advanced personal care electrical appliance industrial park in China, with complete self-production supporting capacity and the introduction of world-class leading fully automatic production equipment. Among them, the Japanese fully automatic Fanuc injection molding machine, ABB and An Chuan robot hand spraying equipment, man-machine separated central feeding system, high-precision stamping system and ultra-precision cutter head grinding equipment have all reached the international leading level.

　　Adhering to the concept of improving the quality of life through technological innovation, Pentium Group put forward the corporate slogan of "Let technology know you better", so as to make product technology closer to consumers, better serve consumers and better understand their needs. In terms of product research and development, Pentium Group has established a three-level R&D system. Enterprise research institute, technology center and quality research center, as well as production technology department constitute a complete enterprise R&D system of Pentium Group from cutting-edge research in the industry to research on brand-new applied technology and product development, and then to research on manufacturing technology.

　　In order to improve the management level and build an all-round competitive advantage, Pentium Group has built an enterprise information management platform in an all-round way, and successfully implemented ERP enterprise resource management system, PDM product research and development management system, CRM customer relationship management system, PCP collaborative office platform system and HR human resource management system. Informatization construction has made the management methods and means of enterprises achieve a qualitative leap, and promoted the scientific and modern decision-making of enterprises.

　　In the future, Pentium will rely on innovative product design and advanced marketing concepts to realize the common value-added with the upstream and downstream value chains, and at the same time, the management team and enterprise employees can reflect their self-value and have expected reasonable returns. Pentium will rely on the three core capabilities of brand, team and product to continuously promote the rapid growth of enterprises and brands, create fashionable and healthy small household appliances for consumers around the world, and run towards a better life together.

Time Network News is directed by Wu Ershan, and the mythical epic film "Feng Shen I" starring ChristianRandPhillips, Li Xuejian, Bo Huang, Yu Shi, Chen Muchi and Na Ran is being released. A few days ago, the film’s director Wu Ershan accepted an exclusive interview with Time.com to share the behind-the-scenes story of the film.

The first part of "Feng Shen" opened the prelude of "Feng Shen Trilogy", which tells the story that Wang Yinshou, a merchant, colluded with da ji, a fox demon, and was tyrannical and heartless, causing a scourge. Jiang Ziya, the immortal of Kunlun Mountain, went down the mountain with the "list of gods" to find a common master in the world to save the whole people. Ji Fa, the son of Xibohou, gradually discovered the true colors of Yin Shou, and turned out to sing songs. The forces of all parties are surging, and the signs of changes are beginning to appear …

The story of "the list of gods" is a household name, and it is also a big IP that many domestic film and television works love very much. Wu Ershan, the director, said, "The core of the story hasn’t changed much, such as the tyranny of the Shang king, the gall of the Wen king, the digging of the heart by Bigan, and the admonition of the Queen Jiang. However, we have to do a new look at the original story from a contemporary perspective and contemporary values, and we have to reorganize his story line and the logic of the story. "

"For example, there is a very important plot in the original, which may be unknown to everyone, and that is why da ji went into the Shang Dynasty to destroy it. Because Yin Shou wrote a poem and molested Nu Wa. Many people don’t know why. What’s wrong? Is it that big? From the perspective of contemporary people, this is nothing, and it is a little bold. According to the current audience in China, this is actually a trivial matter, and it is not enough to overthrow a dynasty. Including da ji, she has been instilling many evil ideas into Yin Shou, and the setting that women are femme fatale. This is unacceptable to the contemporary audience, especially to me. It is very demeaning to women and a concept that is disrespectful to women. These things need to be adjusted and redesigned to make it more in line with our modern people’s feelings and values. "

"For example, I like the Ji Chang family in the original story very much. I like Ji Chang very much, a father who bears the burden of humiliation. But I don’t think the description of him in the original is convincing enough-why did he endure the pain to eat his son’s meat? In the original, he cheated Yin Shou, then escaped and returned to his hometown to survive. But I think this father is too cunning. We reset the logic of his doing this thing in order to protect his second son, because he has already lost a son, and he wants to protect the surviving son. He can only accept such humiliation and do what he doesn’t want to do, and then the son is determined to rescue him. He is not a sly father. "

It has been several years since the start of the project and the release of the first part of the project, so that many viewers have been worried about the fate of this project. However, Wu Ershan said that the progress of the trilogy of deities was basically within his plan. "Three continuous shooting, fairy epic, our original plan is to complete it in 8 to 10 years, because we predict that this work is very difficult. There was no epidemic at that time. We planned for 8 to 10 years at that time, and this year is the tenth year, so I think it is basically objective. "

"The longest film I shot before was" Searching for Dragons ",which took five months. But it took 18 months to make the trilogy of gods. At the peak of our crew, there were 2,800 crew members working at the scene in one day. In a year and a half, more than 8,000 staff members participated in the pre-filming of the film. "

The first part of "Feng Shen" was released smoothly, and many viewers began to care when they could see the second and third parts. Wu Ershan said that if all goes well, the latter two films will be released in the summer of 2024 and the summer of 2025. The structure of the film trilogy is basically the same as that in the mythical story of "deifying": The second part will tell the story of Ji Fa defending his homeland in Xiqi, and Xiqi, under the protection of Jiang Ziya and other Kunlun immortals, fought against the army of Yin and Shang, and defeated the Ten Commandments. The third part tells that Ji Fa ordered 800 vassals to join the Mengjin League, and began to attack. Immortals, such as Yuanshi Tianzun and Tongtian Patriarch, all participated in the final decisive battle, and finally Ji Fa defeated Yin Shou and established the Zhou Dynasty.

On January 8, 2023, the 20th Guangzhou International Automobile Exhibition (hereinafter referred to as "Guangzhou Automobile Exhibition") held in New Year’s Eve came to a successful conclusion. At the same time, the official said that the 21st Guangzhou International Automobile Exhibition will open from November 17th to 26th, 2023.

According to the official, this year’s Guangzhou Auto Show opened the newly-built D-Zone Pavilion of the Canton Fair for the first time, with an exhibition scale of 220,000 square meters, attracting a total of 383,000 visitors.

On the first day of media day, we welcomed the launch, listing and pre-sale of more than 60 heavy new cars. In this summary article, you will see: Great Wall Shanhai Gun, Wei Brand Blue Mountain, Chang An Yi Da, Hongqi H6, brand new Crown SportCross, brand new Crown Sedan, brand new BMW M2, brand new Civic TYPE R and brand new Mazda CX-50, etc. The 20th Guangzhou Auto Show can be said to be a successful conclusion for the automobile circle in 2022.

　　The front face of the 22 Defender new cars is novel, and the headlights on both sides are square and sharp, and they are domineering. The side lines of the body are straight and smooth, running through the front and rear, and they are matched with multi-spoke wheels, which adds a sporty atmosphere. In the rear part of the car, the taillights are designed with rounded corners and squares, which are highly recognizable after lighting. The overall shape has a clear sense of hierarchy.? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

　　If you have any questions about buying a car after 12 years of deep cultivation in the industry, I will answer them for you as soon as possible. Xiaohua 17694861311 with WeChat

　　The Land Rover Defender will be divided into two versions according to the wheelbase, 90 version and 110 version, and each version will be divided into multiple models, including the first limited edition, the top X, and the S, HSE and SE versions. According to the information we have obtained so far, it can be seen that the 110 version that will be listed in China will launch a total of four Defender X, China’s first limited edition, HSE and SE versions.

　　In terms of body size, the 22 Land Rover Defender is 4853mm long, 2008mm wide, 1967mm high, and has a wheelbase of 2587mm. It is positioned as a medium-sized SUV. The car adopts the plan of front double fork arms and rear multi-link independent suspension, integrates the atmosphere hanging system, and the height of the high and low adjustment is limited to 14cm. It has a very small ground clearance of 218mm. With a 38-degree angle and a 40-degree farewell angle, the water depth can reach 0.9 meters. The off-road experience is very powerful.? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ??

　　22款路虎卫士内饰设计变得不再简陋，中控台使用了涂层镁合金材质，进一步提升了内饰的耐用性，新车使用了全新的四辐式方向盘、12.3英寸全液晶仪表、10英寸中控屏幕，空调旋钮带有液晶显示屏，电子挡把位于中控屏下方，使用更加顺手。

　　22款路虎卫士基于全新的极限全地形D7x平台打造，采用轻量化智能全铝架构，独创的整合式承载车身造就最坚固的路虎，为独立式空气悬架和智能化全时四驱系统的完美表现提供了最佳保障。

　　22款欧规卫士2.0两门P300

　　选配：滑动全景，LED大灯，前雾灯，中控11.4寸大屏。

　　标配： 18钢轮LED大灯LED屋灯多功能方向盘带照明化妆镜的遮阳板2区空调电动折叠加热外后视镜，自动变光内后视镜，织物座椅8项可调节前排座椅，（手动-向前/向后，手动-座椅高度，手动-头枕高度，电动-靠背倾斜）180W音响（6个扬声器）TFT液晶仪表显示器，自主紧急制动（AEB）3D环绕影像系统带限速器的巡航控制车道保持辅助泊车辅助360°带自适应限速器的交通标志识别涉水感应全地形系统 有京环

　　添加本人微信朋友圈每天更新大量平行进口车新车上市，配置、报价、图片。

　　您购车有任何不解问题，我会第一时间为您解答。小花花17694861311同微信

　　公司名称：天津恒泰汽车销售有限公司

　　公司地址：天津滨海新区天保大道86号

　　免责声明：以上购车优惠信息由本网综合经销商提供，由于行情因素价格浮动较大，仅供购车参考；其真实性、准确性及合法性由经销商负责，本网站不提供任何保证，亦不承担任何法律责任。

[Autohome Jinan Discount Promotion Channel] brings you the latest car purchase discount information: Currently in Jinan, Jaguar XEL is conducting a strong promotion, with a maximum discount of 101,800 yuan, making the starting price of this luxury intermediate car very attractive, only 215,000 yuan to start. Consumers who want to seize the opportunity of this price reduction, don’t miss it, click "Chatty Car Price" in the quotation form, let’s explore more possible car purchase surprises together.

With its elegant exterior design, the Jaguar XEL shows the perfect fusion of British luxury and sports. On the front face, the ingenious air intake grille adopts the precision design of the Jaguar family, and the delicate chrome trim and matrix LED headlights complement each other, giving the vehicle a strong visual impact. In the overall style, the streamlined body lines and low body posture show the dynamic and power of the XEL, while at the same time losing elegance and refinement, whether in the city street or on the road, it can attract people’s attention.

With its refined body design, the Jaguar XEL presents an elegant side profile. The body size is 4778mm*1850mm*1429mm and the wheelbase reaches 2935mm, which makes the vehicle visually have a large and comfortable interior space. The smooth side lines outline the elegant and dynamic body lines, showing the consistent luxury aesthetic of Jaguar. The front and rear wheel tracks are 1598mm and 1582mm respectively, further enhancing the stability and handling performance. The tire size is 225/45 R18, which complements the dynamic wheel style, creating a unique sporty temperament of the Jaguar XEL.

The Jaguar XEL interior design is exquisite and luxurious, and the steering wheel is wrapped in high-end leather material, which not only provides a good grip, but also supports manual up and down + front and rear adjustment to meet the individual needs of the driver. The 10.2-inch central control screen shows the sense of technology, integrating multimedia system, navigation and phone functions, so that the driver can easily control various functions. The seats are made of imitation leather, which is both comfortable and durable. The main and auxiliary seats support front and rear adjustment, backrest adjustment and multi-directional adjustment, such as high and low adjustment and waist support, to provide passengers with an excellent riding experience. The front seats are also equipped with heating function to ensure extra warmth in cold weather. The overall interior pays attention to detail and texture, creating an elegant and modern driving environment.

Jaguar XEL is equipped with a 2.0T turbocharged engine with an output of 184 kilowatts and a maximum torque of 365 Nm. This power unit has a strong performance of 250 horsepower and is matched with an 8-speed automatic transmission to ensure the ride and power response of the vehicle during driving.

To sum up, the Autohome owner is full of praise for the exterior design of the Jaguar XEL. The fusion of youthful fashion and classic elements, as well as the smooth design of the lines, all add a lot to the car. The owner’s inclusive experience also reflects the XEL’s ingenuity in details, which undoubtedly brings extraordinary visual enjoyment to the driver. Therefore, for consumers who pursue design and driving pleasure, the Jaguar XEL is undoubtedly a worthy choice.

From April 30th to May 2nd, the 2023 Hua Chenyu Mars Concert Chengdu Station officially ended! Hua Chenyu gathered with tens of thousands of fans to start a three-day music carnival. The super shocking visual stage, the free wear of Mars, the tear-jerking two-way rush, and the journey home with the clock in eating and drinking… All of them are haunting, which together constitute a full memory point of the journey to Mars Chengdu, and live up to the distance of thousands of Martians! On the last night of Chengdu Station, fans did their best to shout for Hua Chenyu, pushing the atmosphere of the scene to a high point several times. Under the dream-like stage design, Hua Chenyu released the musical tension to the fullest, singing from 14:07 pm to 22:00 pm for three consecutive days. During the three-day carnival, the romance of "fireworks" went everywhere in both directions, and the family-like relationship made everyone feel happy at first sight, and it has been a long time! The wonderful appearance of the Martian utopia makes all the previous efforts and waiting have color.

Mars playlist carefully arranged to show sincerity "Hope" physical album is about to be launched

In the three-day performance of Chengdu Station, different playlists were configured every day: on the first day of the playlist, Hua Chenyu sang "Mountains and Seas" in the "sea of people", which filled the atmosphere of the May Day holiday; on May 1, in addition to "My Skateboard Shoes 2016", "The Return of the Master", etc., it was also a surprise to prepare a long improvisation for the fans, and the love for the fans was carefully mixed in every music note, making it difficult for every Martian who came to the scene not to be moved; on the last day of the performance, he also covered the song "Can Beautiful Things Happen to Me", which was adapted from Hunan Satellite TV’s top music synthesis "Sound Life Endless Treasure Island Season". The solo performance that night won wide praise and became the "golden song" of the "Three Gong" performance Received praise from the original singing band "Constantine’s Change Ball" Weibo, and the two sides also met friends as singers, officially following each other on Weibo. Now, the live version of the concert is also to make up for his regret of performing on the stage of "Sound Life Never Ending Treasure Island Season". He once said that he hoped that this song would bring healing power to the outside world, "Good things can happen to us!" And through music to export correct values to the outside world, encouraging people to better heal the earth after a short charge on Mars, is also Hua Chenyu’s insistence. On the evening of May 2, Huahua was still at the end of the performance, and it was surprising to reveal that his fifth new singing album "Hope" will be released to the outside world after the holiday. This physical album is still available in USB and CD versions. Hua Chenyu incorporates dialectical thinking into the album, encouraging everyone to immerse themselves in their own dawnism. The release of the physical album explores fantasy and reality in a more realistic form, and will definitely bring an extraordinary musical experience to the outside world.

"Fireworks" go to N tear-jerking performances in both directions, freedom, tolerance and happiness merge into the romantic base color of Mars

In addition to repeatedly polishing the music, stage and styling, and constantly mobilizing the fans’ musical visual ceiling, the Mars Concert also strives to bring the best home experience to fans. On May 2, Hua Chenyu Studio and the official blog of the Mars Concert released the "Welcome Home" poster at 13:14 at the same time. The "Lifetime" arrangement touched every Martian resident, and they shouted: Huahua understands the sense of ritual! On the afternoon of the 2nd, the fans who were drawn to the stage to play mahjong just wore a red Lolita "flower wedding", and ran to the idol they missed through the vast sea of people, filled with romantic details. Fans enjoyed the freedom of dress and spiritual freedom under Huahua’s carefully crafted utopia. Diversity and inclusiveness have also formed the long-standing romantic base color of Mars. Even if you are not a "Martian" in the true sense, it is difficult not to be infected by the atmosphere here. Hua Chenyu said sincerely on the spot: There may be some people who are not my fans, but when you come to Mars, we are family. This is a place where you can get warm after working hard and tired on Earth. He also enjoyed providing such a place for the soul to live, and the prosperity ended. The beauty of Mars scenes still flashed in everyone’s minds repeatedly. The snow of "Meeting When Flowers Fall", the volley ribbons of "Born into the Sun", the aerial roses of Hangzhou Station… "When the flowers fall next year, the flowers of Mars are in full bloom." "Fireworks" has become a part of the romance while fulfilling its promise to create romance.

The 2023 Hua Chenyu Mars Concert Chengdu Station ended successfully, and the short separation of this journey is also the beginning of the next journey. Looking forward to the 2023 Hua Chenyu Mars Concert Wuhan Station, Hua Chenyu will bring tens of thousands of Martians to his hometown in Hubei to continue writing more beautiful chapters on Mars.

1905 movie network feature On February 17, the schedule was adjusted several times

(Hereinafter referred to as "Chinese Ping Pong") I finally meet you.

At the time of writing, the box office exceeded 72 million.

#ChinaPing Pong Box Office #related topics are on Weibo’s trending topic list.

"’A good movie’ is no longer the standard for whether to watch a movie or not.

The’sense of ritual ‘is becoming more and more important,

‘Mystery ‘is also becoming more and more important. "

Some netizens lamented,

It is well known that the title of the "Chinese Ping Pong" story

There is no "mystery" to a certain extent,

Even though the film’s Douban score reached 7.0,

He has achieved the best reputation in his directorial career.

The current box office still has a lot of room for growth.

"Some people say that we are a persuasion team.

I hope that audiences who have such thoughts will come and watch this movie. "

In the face of continuous bad reviews of past works, and even word-of-mouth overdraft,

Deng Chao responded this way during the release.

Compared to previous creations,

He seemed more attentive this time.

Some time ago,

"Deng Yu Group" brought actor Liang Chao as a guest on "China Film Report",

Dialogue movie channel host Roman, intern journalist He Junlin,

Talk about the moments of the film’s creation that took more than a thousand days.

When his father was young, he was a table tennis doubles champion in Chang’an County, Shaanxi Province

Affected by it,

Yu Baimei is also a huge sports fan.

I have always dreamed of making an exciting sports movie.

So he directed "Chinese Ping Pong".

It also became his "dream come true".

The film tells the story of Chinese men’s table tennis hitting rock bottom in the 1990s.

The new coaching team has launched an all-round transformation of them,

Helped the national table tennis team make a comeback at the 1995 Tianjin World Table Tennis Championships.

"An underappreciated coach,

A group of underappreciated players.

The Jedi counterattack at the lowest point. "

Deng Chao said frankly,

He can fully understand the characters in "Chinese Ping Pong".

Because he and Yu Baimei have also experienced failure,

I have experienced being criticized by everyone and ridiculed by online groups.

How hard is it for the underdog to get things done?

He knows very well.

The story of the national table tennis crowd fighting back against the Jedi made the two directors feel the same.

They want to make "Chinese Ping Pong" their own style.

Deng Chao plays the head coach "Dai Minjia" in the film.

He is not technically superb

Therefore, the famous table tennis coaches Shi Zhihao and Li Nan were invited to become "military advisers".

Practice table tennis skills from scratch.

Although he was ready to "suffer".

But wait until the coach says "Come on!"

He "tortured" him for almost two hours in his first class.

This also made Deng Chao shout directly, "I’m about to faint!"

Especially the character "Dai Minjia" is "left-handed".

He felt even more "headache" about it.

How can you ensure that you are comfortable using your left hand?

The solution Deng Chao came up with was,

Whether you eat or play ball,

Let the colleagues around you stare at you closely,

Once he discovered that he was using his right hand,

You need to fine him.

The film took more than 1,000 days from preparation to release.

The crew has always had 18 table tennis professional consultants "sitting on the spot".

Under the guidance of the experts,

Director Yu and Director Deng’s "secret battle" can always offer laughs for everyone.

Liang Chao, who also plays a table tennis coach in the film, broke the news.

Of course,

The source of jokes for the crew is Deng Chao and this pair of "living treasures".

In the film, the scene where Deng Chao is kicked out of bed by Sun Li,

I only took one shot and it passed.

Yu Baimei joked,

This kind of reflects the life experiences of the couple,

I am just their "recorder".

"Sun Li is the best head of the family."

Talking about his wife’s constant company and encouragement,

Deng Chao said emotionally,

Over the years,

I am especially grateful to Sun Li for her silent dedication.

"I think we made a good movie.

If measured by life,

It has a scale. "

With the dedication and dedication of the entire crew,

Deng Chao couldn’t help but sigh in the end,

I hope the movie is dedicated to everyone who is not optimistic.

Shanxi Provincial Market Supervision Administration

Issuing the "About Regulating Online Community Group Buying"business

Notice of guidance on behavior

Jin City Supervision and Regulation Fa [2023] No. 10

Municipal market supervision bureaus and demonstration zone market supervision bureaus:

The "Guiding Opinions on Regulating the Business Behavior of Online Community Group Buying" has been deliberated and adopted at the 15th Director’s Office Meeting of the Provincial Market Supervision Bureau on June 30, 2023, and is hereby issued to you. Please implement it conscientiously.

Shanxi Provincial Market Supervision Administration

July 14, 2023

(This article is published publicly.)

aboutGuiding Opinions on Regulating the Business Behavior of Online Community Group buying

In order to standardize the business behavior of online community group buying, protect the legitimate rights and interests of consumers, maintain the order of online transactions with fair competition, and promote the standardized and healthy development of online community group buying, according to relevant laws and regulations, the following opinions are put forward.

I. General requirements

Guided by the Supreme Leader’s Thought on Socialism with Chinese Characteristics for a New Era, conscientiously study and implement the spirit of the 20th National Congress of the Communist Party of China, fully implement the spirit of the Supreme Leader’s General Secretary’s important instructions on platform economic governance, conscientiously implement the strategic layout and deployment requirements of the Provincial Party Committee and the Provincial Government to build "Digital Shanxi" to achieve "digital transformation", fully grasp the characteristics, laws and development trends of online community group buying, adhere to inclusiveness and prudence, supervision according to law, and coordinated governance, actively explore suitable network community group buying characteristics, and facilitate fair competition in the online market supervision methods, realize the whole chain, all fields, and normalized supervision before and after the event, and promote the healthy and sustainable development of online community group buying norms.

II. Compaction of relevant subject responsibilities

(1) Compacting the responsibility of online community group buying platform operators

1. Fulfill the obligation of market entity registration according to law. Online community group buying platform operators may carry out online community group buying business activities in a self-operated or non-self-operated manner. Platform operators who sell goods or provide services in their own name are self-operated by the platform and shall handle the registration of market entities according to law and bear the civil liability of commodity sales or service providers. Where trading activities need to obtain relevant administrative licenses, they shall obtain administrative licenses according to law before engaging in business activities. Where trading activities require filing, they shall go to the regulatory authority for filing according to law.

Platform operators who carry out online community group buying in a non-self-operated manner shall, in accordance with the Electronic Commerce Law of the People’s Republic of China and other laws, register the platform operators as market entities, and fulfill the responsibilities and obligations of platform operators according to law.

2. Fulfill the obligation of information disclosure according to law. Online community group buying platform operators shall continue to publicize business license information, administrative license information related to their business operations, or link logos of the above information in a prominent position on the homepage.

If online community group buying is carried out in a non-self-operated manner, the actual seller of the product or the actual provider of the service shall be accurately marked to ensure that consumers can view the main information of the actual seller or service provider on each product or service page. If the platform operator fails to indicate or completely indicate the actual seller of the product or the service provider, causing consumers to mistakenly believe that it is the platform operator’s own operation, the platform operator shall bear the corresponding legal responsibility.

Platform operators shall provide technical support for suppliers to fulfill their information disclosure obligations, and urge suppliers to fulfill their information disclosure obligations in accordance with Article 15 of the Electronic Commerce Law of the People’s Republic of China and Article 12 of the Measures for the Supervision and Administration of Online Transactions.

3. Carry out promotions and publicity in compliance with the law. Platform operators shall standardize the organization of online community group buying promotions and related publicity, comply with the requirements of the Interim Provisions on Regulating Promotional Behaviors, and publicize the time limit, method, rules and unfavorable restrictions on consumers in a prominent manner on the webpage.

Platform operators should standardize information release behavior, strictly abide by the "People’s Republic of China Electronic Commerce Law", "People’s Republic of China Advertising Law", "Internet Advertising Management Measures" and other provisions to release information, and shall not deceive or mislead consumers with false or misleading information.

Platform operators shall take measures to prevent and stop illegal advertisements in the process of providing Internet information services, and monitor and investigate the advertising content released by cooperative suppliers using their information services. If illegal advertisements are found, they shall take necessary measures such as notifying corrections, deletion, blocking, and disconnection of published links to stop them, and retain relevant links.

4. Strictly fulfill the obligation of review and verification. Operators of online community group buying platforms shall strengthen the review of business qualifications and commodity certification documents of cooperative suppliers, establish and implement a purchase inspection and acceptance system, and verify product qualification certificates and other marks. When conditions permit, encourage on-site inspections of suppliers’ business sites and production environments.

Platform operators shall require suppliers to provide information such as identity certificates, business licenses, administrative licenses, business addresses, and contact information, and conduct verification and registration, establish registration files, and regularly verify and update them.

Platform operators who conduct online community group buying in a non-self-operated manner uniformly collect order information, collect goods, sort and pack and deliver them to the pickup point, platform operators shall conduct necessary inspections of the goods, and at the same time ensure that the containers, tools and equipment for storing, transporting and loading and unloading food are safe, harmless, kept clean, prevent food contamination, and meet special requirements such as temperature and humidity required to ensure food safety. Food shall not be stored or transported together with toxic and harmful substances. Platform operators who know or should know that the goods sold by suppliers do not meet the requirements for protecting personal and property safety, or have other acts that infringe on the legitimate rights and interests of consumers, and fail to take necessary measures shall be jointly and severally liable with the cooperative supplier according to law.

Platform operators should strengthen the supervision of food safety and improve the food safety management system. The product traceability system should be improved according to the requirements of different categories.

5. Strictly implement the requirements for the protection of consumer rights and interests. Platform operators shall establish and improve a credit evaluation system, provide consumers with a way to evaluate the quality of goods or services sold on the platform and the platform, and shall not hide or delete consumer evaluations. Where consumer evaluations contain information prohibited by laws, administrative regulations and rules from publishing or transmitting information, the platform may deal with it technically according to law. Encourage and guide online community group buying platforms to make use of their own resources and management advantages, and take the initiative to publicize to the public the number of complaints, complaints mediation, reconciliation success rate and other information related to safeguarding the legitimate rights and interests of consumers among operators on the platform.

Platform operators and suppliers shall strictly implement Article 25 of the Law of the People’s Republic of China on the Protection of Consumer Rights and Interests and the Interim Measures for the Return of Goods Purchased Online within Seven Days without Reason, and implement the return of goods within seven days without reason. If consumers request a return within seven days from the receipt of goods, except for goods that cannot be returned without reason according to laws, regulations and rules, the platform and suppliers shall accept the consumer’s return request. Platform operators shall urge and guide suppliers to fulfill the obligation of returning goods without reason within seven days, conduct inspection and supervision, and provide technical support.

Platform operators shall establish a convenient and effective consumer complaint mechanism, disclose information such as complaint methods and complaint channels, accept and handle consumer complaints in a timely manner, and shall not refuse or deliberately delay processing consumers’ reasonable requests without reason.

Encourage and guide platform operators to establish an advance payment system and safeguard measures. When the legitimate rights and interests of consumers are infringed and cannot be compensated, the platform operator shall make advance compensation to the consumer. After the platform operator compensates the consumer, it may recover compensation from the cooperative supplier and the pickup point according to law.

Online community group buying operators (including online community group buying platforms and suppliers) shall fulfill their safety protection obligations to consumers in accordance with the Law of the People’s Republic of China on the Protection of Consumer Rights and Interests. Platform operators who know or should know that the goods sold or services provided by suppliers do not meet the requirements of personal and property safety, or have other acts that infringe on the legitimate rights and interests of consumers, and fail to take necessary measures, shall bear joint and several liability with the supplier according to law.

6. Strictly implement information security responsibilities. Platform operators shall, in accordance with the relevant provisions of cyber security, improve the cyber security management system, implement security protection technical measures, and ensure information security. Platform operators shall comply with the relevant requirements of the Personal Information Protection Law of the People’s Republic of China, and shall not force, frequently, or excessively request user permissions to illegally collect or use consumers’ personal information; Lawfully obtained consumers’ personal information and the trade secrets of other operators shall be kept strictly confidential, and shall not be disclosed, and shall not be provided to others without the consent of the collected person, and shall take necessary measures to prevent the leakage or loss of the obtained information; in the event of or possible leakage or loss of information, remedial measures shall be taken immediately.

After the user terminates the use of its services, the platform operator shall stop the collection and use of the user’s personal information, provide the user with the service of canceling the account, and publicize the cancellation method to the user on the online platform.

7. Strictly implement intellectual property protection obligations. Platform operators shall establish intellectual property protection rules and operate them effectively to protect intellectual property rights in accordance with the law. Platform operators who know or should know that suppliers infringe intellectual property rights shall take necessary measures such as deletion, blocking, disconnecting links, and terminating transactions. Failure to take necessary measures shall be jointly and severally liable with the supplier.

8. Fulfill the obligation of information retention and cooperation supervision according to law. Platform operators shall record and preserve the information on goods and services and transactions published on the platform, and ensure the integrity, confidentiality and availability of the information. The retention time of goods and service information and transaction information shall not be less than three years from the date of completion of the transaction; where laws and regulations provide otherwise, follow their provisions.

When conducting investigations, evidence collection, and other work in accordance with the law, the supervision department requires the platform operator to provide the identity information of suppliers, relevant contracts signed, commodity and service information, transaction information, and statistical data published on the platform, it shall provide, assist, and cooperate. It shall not conceal, prevaricate, obstruct, or refuse.

Platform operators who carry out online community group buying in a non-self-operated manner shall actively cooperate when the regulatory authorities implement commodity sampling inspections, and shall not refuse on the grounds that they do not have ownership of the commodities.

(2) Compaction network community group buying supplier responsibility

9. Obtain business qualifications in accordance with the law. Online community group buying suppliers refer to operators who cooperate with platform operators to sell goods on the platform in their own name, and shall fulfill the obligations of operators on the platform in accordance with the "E-commerce Law of the People’s Republic of China". Suppliers shall go through the registration of market entities in accordance with the law, obtain business licenses and business qualifications for related commodities, and engage in business operations within the scope of business projects. Except for the circumstances of "exemption from registration" in Article 10 of the "E-commerce Law of the People’s Republic of China".

Online community group buying suppliers shall actively cooperate with platform operators, take the initiative to fulfill information publicity obligations in accordance with Article 15 of the E-commerce Law of the People’s Republic of China and Article 12 of the Measures for the Supervision and Administration of Online Transactions, and ensure that consumers can view business license and administrative license information on each product or service page. If the information announced by the supplier changes, the change shall be reported to the platform in a timely manner within 3 working days, and the platform shall complete the verification and update the publicity within 7 working days.

10. Strictly implement food safety responsibilities. Online community groups buying and selling food to suppliers should strictly abide by the relevant provisions of the Food Safety Law of the People’s Republic of China, fulfill the main responsibility of food safety, and improve the relevant food safety systems.

11. Strictly implement product quality and safety responsibilities. Online community groups buying goods sold by suppliers or providing services shall meet the requirements for ensuring personal and property safety, have the performance that the product should have, meet the execution standards indicated on the product or its packaging, and meet the quality conditions indicated by product descriptions, physical samples, etc. It is not allowed to sell counterfeit and shoddy goods and goods that are prohibited from trading or operating on the Internet by laws and regulations.

12. Strictly implement information disclosure obligations. Online community group buying suppliers shall fully, truthfully, accurately and timely disclose product information, including the content of product labels and labels, to protect consumers’ right to know and choose. Online community group buying suppliers shall issue purchase certificates or service documents in accordance with relevant state regulations or business practices. Applications from consumers for shopping certificates or service documents shall not be rejected or attached to conditions.

(3) Compact the responsibility of online community groups buying offline pickup points

13. Have storage conditions. Online community group buying offline pickup points refer to places that cooperate with community group buying platform operators to provide short-term storage and storage of goods, handle pickup for consumers, and assist the platform in providing after-sales services for users. Natural persons and operators who serve as pickup points shall have storage conditions. Commodities with special requirements for temperature and humidity (such as food, edible agricultural products, etc.) shall be equipped with corresponding facilities and equipment (such as refrigeration and freezing equipment, shelves, etc.) and meet food safety requirements. Encourage online community group buying platform operators to develop operators who have obtained business licenses and food business administrative licenses as pickup points.

Prohibition of online community group buying

14. No improper price behavior shall be implemented. Online community group buying operators shall strictly regulate the online community group buying business behavior, reasonably formulate commodity prices according to market conditions, and shall not implement unfair price behaviors such as low-price dumping, price collusion, price gouging, and price fraud.

15. Monopoly shall not be carried out illegally. First, monopoly shall not be carried out through monopoly agreements. Online community group buying operators with competitive relations shall not reach monopoly agreements to implement fixed prices, divide the market, restrict production (sales) volume, restrict new technologies (products), and boycott transactions. Second, they shall not abuse their dominant market position to exclude or restrict competition. They shall not abuse their dominant market position by predatory pricing without justifiable reasons, refusing to trade, tying sales, restricting operators to engage in "two choices" among competitive platforms, and other acts of abusing their dominant market position to exclude or restrict competition. Third, they shall not illegally implement concentration of business operators to exclude or restrict competition.

16. No unfair competition shall be carried out. Community group buying operators shall operate in accordance with the law and compete fairly, and shall not engage in unfair competition such as commercial confusion, commercial slander, and credit speculation. They shall not use technical means to damage the competition order, hinder the normal operation of other market entities, and endanger the market environment of fair competition.

17. Do not use false or misleading methods to deceive and mislead consumers. Online community group buying operators and pick-up point staff shall not fabricate, delete, conceal, induce, force consumer evaluations, or confuse consumer evaluations of different goods (including services, the same below); shall not use false or misleading prices to deceive or induce consumers to trade with them; shall not use false advertising, promotion methods, samples, instructions, standards, certification qualifications and other information to mislead consumers; shall not use false or misleading methods such as fictitious spot, false reservation, false panic buying, etc.

Investigate and punish illegal acts of online community group buying according to law

18. Investigate and deal with e-commerce violations according to law. In response to issues such as the failure to implement the responsibilities of online community group buying platform operators, in accordance with Articles 76, 80, 81 and 83 of the E-Commerce Law of the People’s Republic of China, platform operators shall be investigated and dealt with for failing to fulfill their obligations of information disclosure and information preservation, failing to take necessary measures for platform operators to infringe on consumer rights and interests, failing to fulfill their obligations of qualification review for platform operators, and failing to fulfill their obligations of security protection for consumers.

19. Investigate and punish violations of the legitimate rights and interests of consumers according to law. In response to the infringement of the legitimate rights and interests of consumers in online community group buying, according to Article 56 of the Consumer Rights Protection Law of the People’s Republic of China, focus on investigating and punishing consumers’ requests for replacement, return, replenishment of goods, refund of payment and service fees or compensation for losses, intentional delay or unreasonable refusal and other illegal acts.

20. Investigate and punish monopoly violations according to law. In response to the illegal implementation of monopoly in online community group buying, according to Articles 56, 57 and 58 of the Antimonopoly Act of the People’s Republic of China, focus on investigating and punishing illegal acts such as reaching monopoly agreements, abusing market dominance, and implementing concentration restrictions and excluding competition.

21. Investigate and punish illegal acts of unfair competition according to law. In response to issues of unfair competition such as fictitious transactions, deception, and misleading consumers in online community group buying, according to Articles 18 and 20 of the Anti-Unfair Competition Law of the People’s Republic of China, focus on investigating and punishing illegal acts such as false or misleading propaganda and confusion.

22. Investigate and deal with advertising violations according to law. According to Article 55 of the Advertising Law of the People’s Republic of China, focus on investigating and dealing with online community group buying platforms and platform operators publishing false advertisements that deceive and mislead consumers.

23. Investigate and punish food safety violations according to law. In response to food safety issues in online community group buying, according to Article 126 of the Food Safety Law of the People’s Republic of China, focus on investigating and punishing illegal acts such as unqualified sales of food and failure to establish a purchase inspection system.

24. Investigate and deal with product quality violations according to law. In response to issues such as the sale of counterfeit and shoddy products in online community group buying, in accordance with Articles 49, 50, 51, 52, and 54 of the Product Quality Law of the People’s Republic of China, focus on investigating and punishing illegal acts such as adulteration in products, falsification, shoddy, and substandard products as qualified products.

25. Investigate and deal with unfair price practices according to law. For unfair price practices such as low-price dumping, price collusion, price gouging, and price fraud, they shall be investigated and dealt with in accordance with Articles 14 and 40 of the Price Law of the People’s Republic of China and other laws and regulations.

26. Investigate and punish intellectual property violations according to law. For the infringement of intellectual property rights by online community group buying platforms and suppliers, according to the "Electronic Commerce Law of the People’s Republic of China"And relevant laws, regulations and rules on intellectual property protection shall be investigated and dealt with in accordance with the law.

Local market supervision departments should attach great importance to the supervision of online community group buying and other new forms of online transactions, supervise and guide online community group buying platforms to fulfill their main responsibilities in accordance with the law, take the initiative to carry out self-examination and self-correction, and thoroughly rectify relevant problems in a timely manner. It is necessary to strengthen organizational leadership, give full play to comprehensive law enforcement advantages, and coordinate the strength of various business lines to effectively improve the efficiency and level of online community group buying supervision.

This opinion will come into force on August 15, 2023 for a valid period of 5 years.

Suzhou, China, Palo Alto, California, USA May 20, 2021/PRNewswire/-Genxi Biotechnology Group (NASDAQ: GRCL；; Genxi Bio, a global clinical biopharmaceutical company dedicated to developing efficient and economical cell therapy for cancer treatment, announced today that it will publish the latest clinical research results of a multi-center, first-time human trial on GC012F in the treatment of relapsed/refractory multiple myeloma during the annual meeting of American Society of Clinical Oncology (ASCO) in 2021 and the conference of European Hematology Association (EHA) in 2021.

GC012F is a BCMA/CD19 dual-target autologous CAR-T cell therapy developed based on the patented technology platform of Genxi Bio-FasTCAR, which has the advantage of "production can be completed the next day". At present, the candidate product is being evaluated in a phase I clinical trial initiated by researchers.

• By January 12, 2021, 19 patients with multiple myeloma were enrolled in the three dose groups of this study, of which the highest dose level was 3×10.^fiveCells/kg body weight, all the above patients meet the criteria of recurrence/refractory after multiple rounds of treatment. Subsequent patients (after the release of data at the ASH annual meeting in 2020) received the highest dose level of treatment.
• The early objective remission rate (ORR) was as high as 94.7%(18/19), and all the responses showed that excellent partial remission (VGPR) and even complete remission (SCR) were obtained. The data of all dose groups showed a rapid, in-depth and lasting therapeutic effect.
• All patients (n=9) who received treatment in the highest dose group achieved negative minimal residual lesions-complete remission (MRD- sCR) in a strict sense.
• Of the 19 patients, 18 (94.7%) belonged to the high-risk patients defined in mSMART 3.0 guidelines, and the median number of previous treatment lines was 5.
• 94.7%(18/19) patients have been exposed to PI, IMiD and at least the third treatment scheme, including anti-CD38 targeted therapy.
• The safety of GC012F is consistent with the previous observation results, and the main symptom is low-grade cytokine release syndrome (CRS)(84% patients are grade 1/2; 11% (n=2) patients were grade 3), and there was no grade 4 or 5 CRS；. No immune effector cell-related neurotoxicity (ICANS) was observed in 19 patients. Adverse events (TEAEs) occurred during treatment were mainly manifested as decrease of blood cell count and increase of AST. All TEAEs were relieved after standard treatment.
• The study will continue to evaluate the effectiveness and safety of GC012F in the treatment of patients.

"I am glad to see the mutual evidence between the follow-up of the initial patients and the treatment effect of the subsequent patients, which not only confirms the research results announced at the annual meeting of ASH last year, but also further clarifies the excellent safety and effectiveness of GC012F dual-targeted autologous CAR-T cell therapy, including for high-risk patients."Chief Medical Officer of Genxi BiologydoctorIt said: "High-risk patients are usually extremely difficult to treat, but all patients in the highest dose group in this study have reached the MRD negative sCR state and maintained a deep response for six months or even longer after receiving GC012F infusion. The above exciting research data bring brand-new hope to high-risk patients (including those who do not respond to the standard treatment plan). Next, we plan to promote this research on a global scale, including promoting it as a more preferred treatment option. I look forward to sharing more developments with you in the near future. "

GC012FClinical research initiated by researchers (IIT) Co-principal researcher, Professor Du Fu of shanghai changzheng hospital."Multiple myeloma (MM) is a malignant blood tumor that is extremely difficult to treat. There are about 750,000 patients with multiple myeloma worldwide.^[1]There are about 160,000 new patients every year.^[2]And it is on the rise year by year. Among them, high-risk patients account for 20%-30%.^[3]The prognosis is usually poor, accompanied by higher risk of early recurrence, shorter progression-free survival and overall survival. This time, we are pleased to see that the BCMA/CD19 dual-target autologous CAR-T cell therapy GC012F of Genxi Bio has shown excellent effectiveness and safety for the long-term follow-up results of patients with relapsed/refractory multiple myeloma. And thanks to the advantages of FasTCAR platform, the waiting time of clinical treatment has been significantly shortened, and the hope of life has been ignited for more patients. "

GC012FClinical research initiated by researchers (IIT) Co-principal researcher, Professor Fu Weijun of shanghai changzheng hospital.Said: "I am very happy to see that after we announced the first human trial data of GC012F in the form of oral report at the ASH meeting last year, this research has made positive progress again, and the previous results have been further verified; This also allows us to see the good application prospects of Ganxi Bio-FasTCAR platform and Dual CAR technology. With the deepening of research, the clinical benefits of this innovative BCMA/CD19 dual-targeted autologous CAR-T cell therapy for patients with multiple myeloma, especially high-risk patients, are constantly emerging. It is expected that this research will continue to achieve more results and strive to meet the urgent treatment needs of patients with recurrent/refractory multiple myeloma as soon as possible. "

Details of the electronic poster are as follows:

2021American Society of Clinical Oncology (ASCO) annual meeting

abstract8014：Long-term follow-up results of the first multicenter human trial of BCMA/CD19 dual-target CAR-T cell therapy GC012F for patients with relapsed or refractory multiple myeloma based on FasTCAR platform.

Poster release date:June 4, 2021

2021European hematology association (EHA2021) conference

abstractEP962：Long-term follow-up results of the first multicenter human trial of BCMA/CD19 dual-target CAR-T cell therapy GC012F for patients with relapsed or refractory multiple myeloma based on FasTCAR platform.

Poster release date:June 11th, 2021

About multiple myeloma

Multiple myeloma (MM) is the third most common malignant hematological tumor in the United States. Its tumor cells originated from bone marrow plasma cells, an immune cell responsible for secreting anti-infective antibodies. About 160,000 patients worldwide are diagnosed with multiple myeloma every year; In 2020, the United States is expected to have more than 32,000 confirmed patients. In recent years, although many progress has been made in the treatment of multiple myeloma, the clinical treatment effect is still unsatisfactory. International Myeloma Working Group (IMWG) and the consensus guidelines of Mayo ST Rating for Myeloma and Risk-Adapted Therapy (MSMART) classify patients with specific cytogenetic abnormalities or other abnormalities as high-risk patients, and this group accounts for 20-30% of all patients with multiple myeloma. High-risk patients with high risk of early recurrence, progression-free survival and short overall survival are considered as the most difficult patients with multiple myeloma, and usually have poor prognosis.

aboutGC012F

GC012F is a candidate product for dual-target autologous CAR-T therapy based on FasTCAR platform. At present, the candidate product is evaluating its safety and effectiveness in the treatment of multiple myeloma in a multi-center and phase I clinical trial initiated by researchers, covering many research centers in China. GC012F brings rapid, in-depth and lasting therapeutic effects to patients with multiple myeloma by simultaneously targeting the malignant plasma cell site expressing BCMA and the early progenitor cell site expressing CD19.　

aboutFasTCAR

FasTCAR is a technology platform with intellectual property rights of Genxi Bio, aiming at developing high-quality autologous CAR-T cell therapy. Preclinical studies show that the phenotype of CAR-T cells produced by FasTCAR technology platform is younger, the degree of depletion is lower, and the amplification ability, persistence, bone marrow migration ability and tumor cell clearance activity are enhanced. With the advantage of "completing production the next day", FasTCAR platform technology can greatly improve cell production efficiency, thus significantly reducing production costs and enabling cell therapy to benefit more cancer patients.

About genxi creatures

Genxi Biotechnology Group (Genxi Bio for short) is a global clinical biopharmaceutical company dedicated to the discovery and development of breakthrough cell therapy. Using its pioneering FasTCAR and TruUCAR technology platforms, Genxi Bio is developing a number of rich clinical cancer treatment product pipelines, both autologous and allogeneic. These products are expected to overcome the persistent major industry challenges of traditional CAR-T therapy, including long production time, poor production quality, high treatment cost and lack of effective treatment for solid tumors. To learn more about Genxi Bio, please visit www.gracellbio.com/ Concern LinkedIn account @GracellBio.

Warning statement about forward-looking statements

The statement in the press release about future expectations, plans, prospects and other non-historical facts may contain a "forward-looking statement" as defined in the Private Securities Litigation Reform Act of 1995. These statements include, but are not limited to, statements related to the expected transaction and completion time of this offering. These statements may, but do not necessarily, contain the following words and corresponding negative forms or similar words: purpose, expectation, belief, estimation, prediction, plan, possibility, prospect, plan, potential, conjecture, formulation, seeking, possibility, should and will. Due to various important factors, the actual results may be significantly different from the forward-looking statements, and there is no guarantee that any forward-looking statements will be realized. These important factors include the factors mentioned in the Risk Factors section of Genxi Bio’s recent annual report in Form 20-F, and the discussion on potential risks, uncertainties and other important factors in Genxi Bio’s subsequent report to the US Securities Regulatory Commission after the session. Any forward-looking statements in this statement only reflect the current expectations, and Genxi Bio has no responsibility to publicly update or review any forward-looking statements, whether based on new information, future events or other reasons. Readers are requested not to rely on forward-looking statements after the publication date of this press release.

Media contact

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